The ubiquitin-proteasome system (UPS) regulates intracellular protein degradation, cellular homeostasis, and signal transduction. Therapeutics targeting ubiquitin enzymes—including E3 ligases, deubiquitinating enzymes (DUBs), and Proteolysis Targeting Chimeras (PROTACs)-represent a rapidly expanding frontier in targeted protein degradation for oncology, neurodegeneration, and autoimmune...
English
French
Spanish
Portuguese
Deutsch
Turkish
Dutch
Italiano
Russian
Romaian
Portuguese (Brazil)
Greek